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Search Results for " gpr40 agonist 2 "

11

Compounds

Cat No. Product Name Synonyms Targets
T10507 GPR40 Agonist 2 GPR
GPR40 Agonist 2 is a GPR40 agonist. It can be used in the research of diabetes.
T15810 LY2922470 GPR
LY2922470 reduces glucose levels along with significant enhancements in insulin and GLP-1, which is the potential for the treatment of type 2 diabetes mellitus (T2DM). LY2922470 is an effective, selective, and orally ava...
T60184 TUG-499 GPR , PPAR
TUG-499 is a selective free fatty acid receptor 1 (FFAR1 or GPR40) agonist (EC50: 7.39).TUG-499 has an affinity for FFAR1 or GPR40 over the related receptors FFA2, FFA3 and the nuclear receptor PPARγ, as well as other di...
T11459 GPR40 agonist 1 Others
GPR40 agonist 1 is an effective new GPR40 agonist (EC50s: 17 nM and 2 nM for rGPR40 and hGPR40).
T62542 GPR40 agonist 5
GPR40 agonist 5 is an orally active GPR40 (G protein-coupled receptor 40) agonist (EC50: 47 nM). gPR40 agonist 5 reduces blood glucose levels and improves glucose tolerance. gPR40 agonist 5 shows adequate control of hype...
T14202 AM-4668 GPR
AM-4668 is a type 2 diabetes GPR40 agonist. For GPR40, in A9 cells (GPR40 IP3 assay) and CHO cells (GPR40 aequorin assay), the EC50s are 3.6 nM and 36 nM, respectively.
T69953 MK-8666 Tris
MK-8666 Tris is a partial GPCR agonist that is coordinated with the action of GPR40. MK-8666 has been investigated for treatment of type 2 diabetes mellitus.
T70468 MK-8666
MK-8666 is a partial GPCR agonist that is coordinated with the action of GPR40. MK-8666 has been investigated for treatment of type 2 diabetes mellitus.
T36634 ZQ 16
Selective medium-chain free fatty acid receptor GPR84 agonist (EC50 = 139 nM). Exhibits no response at GPR40, GPR41, GPR119 or GPR120 at 100 μM. Activates calcium mobilization, inhibits cAMP accumulation, and induces ERK...
T73434 BI-2081
BI-2081, a GPR40 (FFAR1) partial agonist with an EC50 of 4 nM, promotes glucose-dependent insulin secretion and lowers plasma glucose levels. This compound is utilized in metabolic disease research, specifically targetin...
T35816 ZLY032
ZLY032 is a dual agonist of free fatty acid receptor 1 (FFAR1/GPR40; EC50= 68 nM in a FLIPR assay) and peroxisome proliferator-activated receptor δ (PPARδ; EC50= 102 nM in a reporter assay).1It is selective for FFAR1 and...
TargetMol